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Discussion on Research Summary: Live Yeast Supplementation Found Beneficial

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Robert N. Oglesby DVM
Moderator
Username: dro

Post Number: 19316
Registered: 1-1997
Posted on Sunday, Oct 7, 2007 - 12:15 pm:   Edit PostPrint Post

Following our last piece of published research, here is a result that comes to a different conclusion: it found improved digestibility of the cellulose portion of the diet in horses supplemented with 10 grams daily (split into two feedings) of a live yeast formulation containing 4.5 billion colony forming units (cfu's) per gram. This would be a daily dose of 45 billion cfu's daily. The supplement also seemed to stimulate appetite. Of course in a time where the biggest problem in horses in obesity this would be a mixed blessing but for those with difficult keepers it may provide a needed boost.
DrO

J Anim Sci. 2007 Oct 2;
Effect of live yeast culture supplementation on apparent digestibility and rate of passage in horses fed a high-fiber or high-starch diet.

Jouany JP, Gobert J, Medina B, Bertin G, Julliand V.

INRA, UR1213 Herbivores, Site de Theix, 63122 Saint Genes Champanelle.

Eight crossbred male horses aged 12 +/- 5 years and weighing 305 +/- 18 kg were used in pairs in a 4 x 4 Latin square design with 4 ground and pelleted diets. Each pair included a cecum and right-ventral colon-fistulated animal and a cecal-fistulated animal. The 4 horse diets were: a high-fiber diet (HF+0), based on dehydrated alfalfa, a high-starch diet based on barley and wheat bran (HS+0), and either the HF or HS diet supplemented with Saccharomyces cerevisiae (SC) CBS 493.94 (HF+SC and HS+SC). The probiotic preparation contained 4.5 x 10(9) cfu.g(-1) of live yeast mixed with the culture medium, and was top-dressed on to feed pellets at a rate of 10 g.d(-1), equally distributed between the 2 daily meals. All 4 diets were offered in the same quantities [18.0 g of pelleted feed DM + 3.5 g of long wheat straw.kg BW(-1).d(-1)]. Each of the 4 experimental treatments was divided into a 21-d period of diet adaptation followed by a 10-d period of total fecal collection for digesta flow rate and apparent digestibility measurements. Three markers were used to measure mean retention time (MRT) of feed particles: Yb bound to the pelleted feeds for MRT in the whole digestive tract (MRTYb), Eu bound to the pelleted feeds, and Dy bound to the fecal particles for MRT in the hindgut (MRTEu and MRTDy). Apparent digestibilities of DM, OM, and CP were greater (P < 0.001) in the HS than HF diet, independently of SC supplementation; whereas, ADF digestibility was greatest in the HF diet (P = 0.035). Cellulolytic activity estimated through the in vitro disappearance rate of dietary ADF fraction (IVADADF) was lesser (P < 0.001) in the HS than HF diet. There was no dietary effect on NDF digestibility due to the longer MRTEu of small particles in the hindgut (P = 0.036), which compensated for the lower fibrolytic activity expressed per unit of time in HS compared to HF diet. SC supplementation improved ADF digestibility (P = 0.038) and stimulated DM (P = 0.030) and NDF (P = 0.038) intakes, but had no effect on the MRT of solid digesta. The absence of any significant diet x SC interaction supports the strategy of using SC to stimulate cellulose digestion and improve the nutritional status of horses under both HF and HS diets.
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Holly Wood
Member
Username: hwood

Post Number: 2358
Registered: 3-2001
Posted on Sunday, Oct 7, 2007 - 12:58 pm:   Edit PostPrint Post

Dr. O.,
Do the pro/pre-biotic supplements state "cfu"s on the labels or is there another measurement that we should consider? If so, how does it compare? I may be include a probiotic in my pony's diet, but don't want to waste money on one that doesn't provide the maximum amount per recommended measurement.
Thank you.
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Robert N. Oglesby DVM
Moderator
Username: dro

Post Number: 19325
Registered: 1-1997
Posted on Monday, Oct 8, 2007 - 7:41 am:   Edit PostPrint Post

I do not know of any other measure of live organism content placed on nutraceuticals and any product that is designed as a live yeast probiotic should contain the cfu's. I would be very suspicious of anything that just says "contain live cultures". As that really has no meaning.
DrO
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