Weakness is a very general symptom and can have many causes and may be confused with depression and incoordination:
* Depression is when a horse is not as alert as normal and can vary from mild to the point he is not reacting to you. It is a symptom of central nervous disease, pain, or fever.
* Incoordination is when the muscles are strong but the horse is unable to stand straight or travel straight and is also a sign of disease of the nervous system.
* More on Diseases of the Nervous System.

Causes of weakness include: exhaustion, diseases of the muscle, peripheral nerves, neuro-muscular junction, and electrolyte abnormalities. The following diseases are when muscular weakness is a predominant symptom.

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