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Equine Cushing's Disease and Pituitary Pars Intermedia Dysfunction (PPID) in Horses
  by Robert N. Oglesby DVM


Introduction » Symptoms » Cause » Diagnosis » Treatment » Prognosis » More Info 

Common signs of aging in horses includes:
  • Long shaggy coats (hirsutism) that do not shed out,
  • Decreased energy levels with mild to moderate depression,
  • Weight loss, muscle wasting, abnormally deposited fat along the topline of the neck and tail head.
  • A tendency to founder
These signs and others are commonly caused by hormone secreting tumors of the pars intermedia portion of the pituitary gland and the disease has come to be called Equine Cushing's(EC) or more appropriately Pituitary Pars Intermedia Dysfunction (PPID). This disease may affect 70% of all horses by the time they reach 30 and has been documented in horses as young as eight years. The disease is rare however in horses under 13 years of age and most often diagnosed in those over 18.

The tumors produce chemicals with hormonal effects that result in altered metabolism. This article discusses clinical signs, symptoms, diagnosis. and treatments, including the herbal product Horminase (Vitex angus-castus).
      ~Word Count: 4407 words (The average magazine page contains about 600 words);
      ~Last Updated: July 10, 2015;
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Discussions on Pituitary Pars Intermedia Dysfunction (PPID): Equine Cushing's
  Titles Subtopics Posts Updated
iconEarly Treatment for PPID?Mar 14, 19
iconResearch Summary: Metabolic Syndrome, Obesity and soaking hayOct 3, 15
iconFeed program for thin Cushinoid horseJun 4, 13
iconResearch Summary: Cushings (PPID) in the TropicsFeb 12, 13
iconCushings Horse Looks Unable to Get Up35 Jan 31, 13
iconCan I be sure he has Cushings from Aug ACTH test?Sep 21, 12
iconResting tachypnea (40) and RR 100+ with moderate exercise-cushings ...Apr 23, 12
iconCushings horse with Enlarged SpleenApr 2, 12
iconFeeding oil to a Cushings horseFeb 12, 12
iconIs it cushings??Sep 12, 11
iconCushinoid horse with continued exercise intoleranceAug 13, 11
iconResearch Summary: Diagnosis of PPID May 25, 11
iconCushings Disease - 25 yr old Mare not cycling symptomatic of Cushings?Apr 24, 11
iconCan pergolide raise insulin?23 Nov 13, 10
iconPergoglide dosage67 Oct 2, 10
iconPergoglideMay 6, 10
iconDo CD Horses shed differently on pergolide64 Aug 8, 10
iconDoes Cushings = founder?Jan 23, 10
iconPergolide aversion19 Jan 22, 10
iconDramatic weight loss, Cushings?42 Jul 1, 11
iconIs Cushings causing this?79 Jan 8, 10
iconOld pony with CushingsOct 14, 09
iconMissed pergolide doses?Oct 1, 09
iconIs it time for pergolide?113 Sep 6, 10
iconSlow to shed winter coatOct 8, 09
iconPossible Cushings - test and medicate or manage?Jun 17, 09
iconResearch Study: Stability of Compounded PergolideApr 8, 09
iconBoosting immunity in Cushings horses?12 Apr 7, 09
iconPossible Cushings Horse Respiratory Issues during the summerFeb 26, 09
iconFeeding an Insulin Resistant Horse with few/poor teethJan 29, 09
iconAllergies produced by PergolideNov 17, 08
iconDifferential diagnosis of possibly cushingoid horseAug 20, 08
iconPergolide/persistence in manure/broodmare coprophagiaMay 7, 08
iconCushings and hock injectionsMay 6, 08
iconGlucosamine and Chondroitin and CushingsMar 16, 08
iconNew Cushings Diagnosis13 Jan 25, 08
icon"Propensity" for Cushing's Disease14 Jul 26, 10
iconCushingoid/IR pony hoof pain38 Nov 15, 07
iconPergolide being withdrawn from the market11 May 15, 07
iconPergolide - Cushings - New FindingsMar 31, 07
iconCushings - but no history of laminitis.Feb 21, 07
iconCushings in an easy keeper?18 Sep 18, 06
icon28 yo TB mare suspected Cushings67 Jan 30, 07
iconCushings? Could it be lighting?Jul 18, 06
iconChange of climate for potentially Cushinoid mare24 Nov 13, 06
iconCushingoid mare declining - need helpApr 13, 06
iconPony with Cushings/IR has painApr 10, 06
iconPregnant Mare with CushingsMar 20, 06
iconCushing's and massage16 Feb 9, 06
iconDex Suppression and LaminitisSep 12, 07
iconCushings and homeopathyDec 22, 05
iconYoung horse with chushingsAug 5, 05
iconCushings ScreenJun 2, 05
iconHairy horseJan 21, 06
iconVariation in ACTH and dex suppression test with seasonMay 19, 05
iconTesting for Cushing'sApr 7, 05
iconCushing in Young HorseApr 2, 06
iconEvitex -formerly HormoniseFeb 22, 05
iconVery Itchy Cushings HorsesSep 23, 04
iconCushing's diagnosisJun 5, 04
iconCortisol Ryhthm and CushingsApr 10, 05
iconAlteration of Pergolide dose - negative response.Jan 19, 04
iconPeripheral CushingsDec 8, 03
iconIs it more than cushings?25 Nov 3, 09
iconFlu shots and Cushing'sOct 24, 03
iconCushings and Nutrition33 Apr 7, 06
iconLess expensive source for pergolide!24 Oct 10, 09
iconBlood Profile for Cushingoid and ACTH values15 Mar 4, 03
iconDiagnosis of TumorMay 22, 04
iconArchived DiscussionsClick link to access data.
iconCushings and Insulin ResistanceSep 14, 04
iconCushings and behavior changesSep 20, 03
iconExcessive sweatingFeb 7, 08
iconNot shedding - diagnostic procedures10 Mar 17, 03
iconElevated InsulinMar 18, 03
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