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Equine Cushing's Disease and Pituitary Pars Intermedia Dysfunction (PID) in Horses
by Robert N. Oglesby DVM
Introduction
Introduction
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Symptoms
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Cause
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Diagnosis
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Treatment
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Prognosis
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More Info
Common signs of aging in horses includes:
- Long shaggy coats (hirsutism) that do not shed out,
- Decreased energy levels with mild to moderate depression,
- Weight loss, muscle wasting, abnormally deposited fat along the topline of the neck and tail head.
- A tendency to founder
These signs and others are commonly caused by hormone secreting tumors of the pars intermedia portion of the pituitary gland and the disease has come to be called Equine Cushing's(EC) or more appropriately Pituitary Pars Intermedia Dysfunction (PPID). This disease may affect 70% of all horses by the time they reach 30 and has been documented in horses as young as eight years. The disease is rare however in horses under 13 years of age and most often diagnosed in those over 18.
The tumors produce chemicals with hormonal effects that result in altered metabolism. This article discusses clinical signs, symptoms, diagnosis. and treatments, including the herbal product Horminase (Vitex angus-castus).
~Word Count: 4347 words (The average magazine page contains about 600 words);
~Last Updated: October 15, 2009;
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Discussions on Cushing's Syndrome and Pituitary Tumors
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Titles |
Subtopics |
Posts |
Updated |
 | Old pony with Cushings | 1 | 7 | Oct 14, 09 |
| Missed pergolide doses? | 1 | 3 | Oct 1, 09 |
| Is it time for pergolide? | 1 | 78 | Nov 20, 09 |
| Slow to shed winter coat | 1 | 5 | Oct 8, 09 |
| Possible Cushings - test and medicate or manage? | 1 | 7 | Jun 17, 09 |
| Research Study: Stability of Compounded Pergolide | 1 | 1 | Apr 8, 09 |
| Boosting immunity in Cushings horses? | 1 | 12 | Apr 7, 09 |
| Possible Cushings Horse Respiratory Issues during the summer | 1 | 3 | Feb 26, 09 |
| Feeding an Insulin Resistant Horse with few/poor teeth | 1 | 4 | Jan 29, 09 |
| Allergies produced by Pergolide | 1 | 7 | Nov 17, 08 |
| Differential diagnosis of possibly cushingoid horse | 1 | 7 | Aug 20, 08 |
| Pergolide/persistence in manure/broodmare coprophagia | 1 | 2 | May 7, 08 |
| Cushings and hock injections | 1 | 2 | May 6, 08 |
| Glucosamine and Chondroitin and Cushings | 1 | 3 | Mar 16, 08 |
| New Cushings Diagnosis | 1 | 13 | Jan 25, 08 |
| "Propensity" for Cushing's Disease | 1 | 12 | Nov 17, 07 |
| Cushingoid/IR pony hoof pain | 1 | 38 | Nov 15, 07 |
| Pergolide being withdrawn from the market | 1 | 11 | May 15, 07 |
| Pergolide - Cushings - New Findings | 1 | 7 | Mar 31, 07 |
| Cushings - but no history of laminitis. | 1 | 3 | Feb 21, 07 |
| Cushings in an easy keeper? | 1 | 18 | Sep 18, 06 |
| 28 yo TB mare suspected Cushings | 1 | 67 | Jan 30, 07 |
| Cushings? Could it be lighting? | 1 | 2 | Jul 18, 06 |
| Change of climate for potentially Cushinoid mare | 1 | 24 | Nov 13, 06 |
| Cushingoid mare declining - need help | 1 | 3 | Apr 13, 06 |
| Pony with Cushings/IR has pain | 1 | 9 | Apr 10, 06 |
| Pregnant Mare with Cushings | 1 | 2 | Mar 20, 06 |
| Cushing's and massage | 1 | 16 | Feb 9, 06 |
| Dex Suppression and Laminitis | 1 | 9 | Sep 12, 07 |
| Cushings and homeopathy | 1 | 3 | Dec 22, 05 |
| Young horse with chushings | 1 | 6 | Aug 5, 05 |
| SPECIAL FEED FOR CUSHINGS/FOUNDER HORSES? | 1 | 10 | Dec 29, 08 |
| Cushings Screen | 1 | 4 | Jun 2, 05 |
| Hairy horse | 1 | 8 | Jan 21, 06 |
| Variation in ACTH and dex suppression test with season | 1 | 1 | May 19, 05 |
| Testing for Cushing's | 1 | 7 | Apr 7, 05 |
| Cushing in Young Horse | 1 | 4 | Apr 2, 06 |
| Evitex -formerly Hormonise | 1 | 5 | Feb 22, 05 |
| Very Itchy Cushings Horses | 1 | 6 | Sep 23, 04 |
| Cushing's diagnosis | 1 | 3 | Jun 5, 04 |
| Cortisol Ryhthm and Cushings | 1 | 9 | Apr 10, 05 |
| Alteration of Pergolide dose - negative response. | 1 | 2 | Jan 19, 04 |
| Peripheral Cushings | 1 | 3 | Dec 8, 03 |
| Is it more than cushings? | 1 | 25 | Nov 3, 09 |
| Flu shots and Cushing's | 1 | 4 | Oct 24, 03 |
| Cushings and Nutrition | 1 | 33 | Apr 7, 06 |
| Less expensive source for pergolide! | 1 | 24 | Oct 10, 09 |
| Blood Profile for Cushingoid and ACTH values | 1 | 15 | Mar 4, 03 |
| Diagnosis of Tumor | 1 | 4 | May 22, 04 |
 | Archived Discussions | Click link to access data. |
| Cushings and Insulin Resistance | 1 | 2 | Sep 14, 04 |
| Cushings and behavior changes | 1 | 4 | Sep 20, 03 |
| Excessive sweating | 1 | 2 | Feb 7, 08 |
| Not shedding - diagnostic procedures | 1 | 10 | Mar 17, 03 |
| Elevated Insulin | 1 | 3 | Mar 18, 03 |
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