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Equine Cushing's Disease and Pars Intermedia Dysfunction (PID) in Horses
by Robert N. Oglesby DVM
Introduction
Introduction
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Symptoms
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Cause
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Diagnosis
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Treatment
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Prognosis
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More Info
Common signs of aging in horses are: decreased energy levels, mild to moderate depression, long shaggy coats (hirsutism) that do not shed out, weight loss and muscle wasting, excessive thirst and urination, chronic founder, and excessive sweating. A common cause of some of the signs of aging in older horses is tumors of the pars intermedia of the pituitary gland. This disease may affect 70% of all horses by the time they reach 30 and has been documented in horses as young as eight years. Commonly the onset of symptoms occurs in the late teens to early 20's. The tumors produce chemicals with hormonal effects that result in altered metabolism. Unlike Cushing's Syndrome in other species blood cortisol levels may be normal to decreased making the term Pars Intermedia Dysfunction (PID) preferable. This article discusses clinical signs, symptoms, diagnosis. and treatments, including the herbal product Horminase (Vitex angus-castus).
~Word Count: 4132 words (The average magazine page contains about 600 words);
~Last Updated: May 28, 2008;
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Discussions on Cushing's Syndrome and Pituitary Tumors
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Subtopics |
Posts |
Updated |
 | Differential diagnosis of possibly cushingoid horse | 1 | 7 | Aug 20, 08 |
| Pergolide/persistence in manure/broodmare coprophagia | 1 | 2 | May 7, 08 |
| Cushings and hock injections | 1 | 2 | May 6, 08 |
| Glucosamine and Chondroitin and Cushings | 1 | 3 | Mar 16, 08 |
| New Cushings Diagnosis | 1 | 13 | Jan 25, 08 |
| "Propensity" for Cushing's Disease | 1 | 12 | Nov 17, 07 |
| Cushingoid/IR pony hoof pain | 1 | 38 | Nov 15, 07 |
| Pergolide being withdrawn from the market | 1 | 11 | May 15, 07 |
| Pergolide - Cushings - New Findings | 1 | 7 | Mar 31, 07 |
| Cushings - but no history of laminitis. | 1 | 3 | Feb 21, 07 |
| Cushings in an easy keeper? | 1 | 18 | Sep 18, 06 |
| 28 yo TB mare suspected Cushings | 1 | 67 | Jan 30, 07 |
| Cushings? Could it be lighting? | 1 | 2 | Jul 18, 06 |
| Change of climate for potentially Cushinoid mare | 1 | 24 | Nov 13, 06 |
| Cushingoid mare declining - need help | 1 | 3 | Apr 13, 06 |
| Pony with Cushings/IR has pain | 1 | 9 | Apr 10, 06 |
| Pregnant Mare with Cushings | 1 | 2 | Mar 20, 06 |
| Cushing's and massage | 1 | 16 | Feb 9, 06 |
| Dex Suppression and Laminitis | 1 | 9 | Sep 12, 07 |
| Cushings and homeopathy | 1 | 3 | Dec 22, 05 |
| Young horse with chushings | 1 | 6 | Aug 5, 05 |
| SPECIAL FEED FOR CUSHINGS/FOUNDER HORSES? | 1 | 8 | Jun 24, 05 |
| Cushings Screen | 1 | 4 | Jun 2, 05 |
| Hairy horse | 1 | 8 | Jan 21, 06 |
| Variation in ACTH and dex suppression test with season | 1 | 1 | May 19, 05 |
| Testing for Cushing's | 1 | 7 | Apr 7, 05 |
| Cushing in Young Horse | 1 | 4 | Apr 2, 06 |
| Evitex -formerly Hormonise | 1 | 5 | Feb 22, 05 |
| Very Itchy Cushings Horses | 1 | 6 | Sep 23, 04 |
| Cushing's diagnosis | 1 | 3 | Jun 5, 04 |
| Cortisol Ryhthm and Cushings | 1 | 9 | Apr 10, 05 |
| Alteration of Pergolide dose - negative response. | 1 | 2 | Jan 19, 04 |
| Peripheral Cushings | 1 | 3 | Dec 8, 03 |
| Is it more than cushings? | 1 | 23 | Nov 6, 06 |
| Flu shots and Cushing's | 1 | 4 | Oct 24, 03 |
| Cushings and Nutrition | 1 | 33 | Apr 7, 06 |
| Less expensive source for pergolide! | 1 | 11 | May 28, 06 |
| Blood Profile for Cushingoid and ACTH values | 1 | 15 | Mar 4, 03 |
| Diagnosis of Tumor | 1 | 4 | May 22, 04 |
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