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Discussion on More Information on Squamous Cell Carcinoma

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Sylvia Son
Posted on Tuesday, Feb 1, 2000 - 3:20 pm:   Edit PostPrint Post

Dr. O: I was cruising around your site and found your article on Squamous Cell Carcinoma. This sounds like what I have been treating one of my charges for. He was seen by a vet for a bump (resembles cauliflower)at the very back of his sheath. The vet didn't culture it or call it by name but was convinced, by the feel of it, that it was indeed cancer - my ole guy wouldnt drop for him even after 2 shots of 3cc each of Ace. He recommended we mix a full jar of furazone with a large tube each of Neosporin and Cortisone 10 and 1/2 tube of zimecerin. I was to clean him everyday for 1 week with Ivory liquid, rinse very well, coat inside of sheath with K-Y Jelly then coat the inside of the sheath and up inside all around the penis with the furazone mixture. This treatment was to continue twice a week - which I've been doing now for a few months. The only change I see is that the bump is increasing in size and he's quite uncomfortable when he has to squeeze past this thing to drop (he kicks up toward his under-side. The only option offered was removal his penis. I will be very interested in your comments and especially anything that you may offer that will further help my guy.

Thanks!
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Robert N. Oglesby DVM
Posted on Wednesday, Feb 2, 2000 - 8:09 am:   Edit PostPrint Post

Why would the penis need to be removed if it is on the sheath? If the topical treatment is not working and it is thought to be SCC, I strongly suggest surgical removal and a histocytology done on the removed tumor to verify what it is.
DrO
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Sylvia Son
Posted on Wednesday, Feb 2, 2000 - 10:41 am:   Edit PostPrint Post

Dr. O, I take care of the horse and wasn't able to be present when the horse was see as he was at a location far from my home. When I was told that the vet said what he said I was surprised. I'm no vet, but I don't see how this thing could be operable due to where it's located. I wish I knew the medical terms then I could tell you exactly, it's exact location. It is right at the point that the penis enters the deepst part of the sheath and the sheath folds back around the penis. I know this will sound stupid to a real horseperson (the coach laughed at me when I tried to explain this to the kids we teach) but I visualize the area where the penis is, at it deepest point, as a cave and the tumor is like a big boulder that is half blocking the entrance. When this horse is fully dropped it does appear to be on the upper most part of the penis - it just clears his body...I dunno.
I was wondering about the Fluorouracil and the Furazone, are these similar medications - when I saw the Flurorouracil being mentioned in one of the other posts, I wondered if we might have misunderstood and bought the wrong stuff by mistake (Furazone). If they are different, shouldn't we get the Fluorouracil for better results?
No matter what, I have to tell you that I get frustrated with some of what I consider, imcomplete treatment information.

Thanks Dr. O
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Robert N. Oglesby DVM
Posted on Thursday, Feb 3, 2000 - 3:05 pm:   Edit PostPrint Post

Sylvia,
I am sorry, but trying to answer questions correctly first hand is hard enough without spinning wheels on second and third hand information. Trust me if it is SCC surgery can be done there but a diagnosis needs to be done before treatment is discussed.
DrO
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Sylvia Son
Posted on Thursday, Feb 3, 2000 - 3:43 pm:   Edit PostPrint Post

Dr. O: I apologize! I understand. I just so wanted to find some hope for those of us that love that horse, and some comfort for him.

Thanks for all.
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Marilyn J. Boyd
Member
Username: Mboyd

Post Number: 2
Registered: 2-2005
Posted on Friday, Apr 1, 2005 - 7:09 pm:   Edit PostPrint Post

A 29 year old Thorouhbred in my barn was diagnosed with squamous cell carcinoma on his penis. He has had recuurent "warts" that have been removed on an annual basis by another vet. The vet who saw him today is an equine specialist who said the other vet probably didn't properly diagnose the problem. Are there realistic treatment options for a 29-year old? Would it have been more treatable if the other vet had properly diagnosed it 5 years ago? I promise I won't try to get the other vet in trouble, I'm just curious.
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Robert N. Oglesby DVM
Moderator
Username: Dro

Post Number: 12458
Registered: 1-1997
Posted on Saturday, Apr 2, 2005 - 11:11 am:   Edit PostPrint Post

There is not enough information in your posts to know Marilyn if the previous lesions were SCC or not or whether the current case is going to be a treatment challenge. Warty lesions that are not ulcerated may not be SCC but regular sarcoids.

For information on proper treatment see the article associated with this discussion, Equine Diseases » Skin Diseases » Bumps / Nodules / Warts / Tumors » Squamous Cell Carcinoma.
DrO
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Jacqueline B Gambino
New Member
Username: jackgam

Post Number: 1
Registered: 4-2009
Posted on Tuesday, Apr 28, 2009 - 3:43 pm:   Edit PostPrint Post

My 17 yo gelding has been biopsied for warts on his penis in 2005 and they came back with a benign papilloma from the lab. Today, he had a vet visit including sheath cleaning. It now has a dark spot and a growth around his urethra, which is new. I have a feeling that the vet will remove the growths and do another lab. I read about using an ointment for humans by the name of imiquimod for treatment of SCC on human penises. Would this be a consideration for horses? They comment on the resultant irritation, but that it is ultimately effective.
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Robert N. Oglesby DVM
Moderator
Username: dro

Post Number: 22878
Registered: 1-1997
Posted on Wednesday, Apr 29, 2009 - 7:13 am:   Edit PostPrint Post

Welcome Jacqueline,
There has been no research on SCC in horses so difficult to say. Swelling of the penis and prepuce are major complications of the horse that is in part because of the dependent nature of the organs: once edema forms there in no place for the swelling to go and can be quite a therapeutic challenge. The complications of the irritation may be more severe in the horse than the human.
DrO
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