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Dinoprost: Lutalyse and Synchrocept Use in Horses

  by Robert N. Oglesby DVM


Introduction » Contraindications » Toxicity and Adverse Reactions » Dosage » DRUG REGULATIONS: ARCI Class: Unclassified » More Info 

Lutalyse and Synchrocept are name brands for dinoprost which is also known as dinoprost trometamol or prostaglandin F 2alpha tromethamine. Prostaglandin F 2-alpha has several pharmacologic effects on the female reproductive system, including stimulation of myometrial activity, relaxation of the cervix, inhibition of steroidogenesis by corpora lutea, and can potentially lyse corpora lutea. In horses it is used clinically to:
  • To terminate diestrus and bring a mare back into heat.
  • Abort an embryo before day 35 of pregnancy or a ferus up to around day 100.
  • To terminate a persistent corpus luteum (false pregnancy).

This article is about the contraindications, toxic effects, dosages, and association drug rules that apply to this medication.
      ~Word Count: 1019 words (The average magazine page contains about 600 words);
      ~Last Updated: July 10, 2015;
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Discussions on Dinoprost, Lutalyse, Synchrocept
  Titles Subtopics Posts Updated
iconMare not in standing heat on day 10 post lutalyse??Jul 9, 15
iconGive Lutalyse or Not?May 28, 09
iconUse of prostaglandins with poniesMar 8, 07
iconWhy isn't lutalyse working in this mareSep 14, 06
iconLutalyse in pregnant mareApr 1, 04
iconLutalyse with follicle already present15 Jul 31, 03
iconProstaglandin and gonadotropin.......................Jul 29, 01
iconDinoprost etc. - not sure if safe for my mareMay 14, 01
icon'Morning after pill for horses?!'Apr 16, 00
iconAborting fetus in young mareMar 14, 00
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