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Dinoprost: Lutalyse and Synchrocept Use in Horses
by Robert N. Oglesby DVM
Introduction
Introduction
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Contraindications
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Toxicity and Adverse Reactions
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Dosage
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DRUG REGULATIONS: ARCI Class: Unclassified
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More Info
Lutalyse and Synchrocept are name brands for dinoprost which is also known as dinoprost trometamol or prostaglandin F 2alpha tromethamine. Prostaglandin F 2-alpha has several pharmacologic effects on the female reproductive system, including stimulation of myometrial activity, relaxation of the cervix, inhibition of steroidogenesis by corpora lutea, and can potentially lyse corpora lutea. In horses it is used clinically to:
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To terminate diestrus and bring a mare back into heat.
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Abort an embryo before day 35 of pregnancy or a ferus up to around day 100.
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To terminate a persistent corpus luteum (false pregnancy).
This article is about the contraindications, toxic effects, dosages, and association drug rules that apply to this medication.
~Word Count: 1019 words (The average magazine page contains about 600 words);
~Last Updated: May 28, 2008;
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Discussions on Dinoprost, Lutalyse, Synchrocept
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Subtopics |
Posts |
Updated |
 | Use of prostaglandins with ponies | 1 | 2 | Mar 8, 07 |
| Why isn't lutalyse working in this mare | 1 | 5 | Sep 14, 06 |
| Lutalyse in pregnant mare | 1 | 3 | Apr 1, 04 |
| Lutalyse with follicle already present | 1 | 15 | Jul 31, 03 |
| Prostaglandin and gonadotropin....................... | 1 | 2 | Jul 29, 01 |
| Dinoprost etc. - not sure if safe for my mare | 1 | 3 | May 14, 01 |
| 'Morning after pill for horses?!' | 1 | 4 | Apr 16, 00 |
| Aborting fetus in young mare | 1 | 3 | Mar 14, 00 |
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