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Discussion on Anti-inflammatories - any ideas what I could use? | |
Author | Message |
Member: Cara2 |
Posted on Friday, Dec 20, 2002 - 9:51 am: Hi Dr O,My silly epileptic horse has foreleg lameness and her sesamoid area is sore according to the farrier so we are assuming a strain to one of the ligaments running across the bones. I know from past experience that medicating her successfully is difficult due to her intake of phenobarbitol - this "blocks" other drugs rendering them useless. So far all the treatment my vet can suggest has been rest, cold water and support bandages. The healing process is likely to be slower than if she could be given an anti-inflammatory drug and she is climbing up her stable walls already. Can you suggest anything I could use that would work at all? I was looking forward to our annual ride on Christmas Day - looks like I'll be out on my own two feet instead . Happy Christmas to you all anyway. Thanks Helen |
Member: Westks |
Posted on Friday, Dec 20, 2002 - 11:04 am: DR'O Please correct me if this is a bad idea but I would try DMSO topically on leg. |
Member: Cara2 |
Posted on Friday, Dec 20, 2002 - 11:43 am: Hi Janette,I read up about DMSO and it seems like pretty evil if effective stuff! I'm not sure about its availability in the UK either. |
Member: Paul303 |
Posted on Friday, Dec 20, 2002 - 10:09 pm: Hi Helen, It's used quite a lot over here. As long as you use it judiciously and wear gloves, it can be a wonderful treatment aid. I have no idea about it's usage in conjunction with epilepsy...that's the good Dr.'s call....but in over 20 years, I've never been without it. I don't have need of it often, but I like to keep it around. |
Moderator: DrO |
Posted on Saturday, Dec 21, 2002 - 12:45 pm: I agree with the above painting with a little DMSO might be of benefit but the results of such on the blood levels of phenobarb are unknown.Though I cannot find any problems in the literature of concomitant barbituate and NSAID's use (and this is studied a lot) an effect is not surprising with two drugs so highly plasma bound. My guess is that the NSAID's do not block the actions of the phenobarb but that they change the pharmockinetics: the rates which the body eliminates the drug. It does seem likely that the bute would decrease plasma binding and increase the rate of excretion. Higher doses may be required during its use. DrO |
Member: Cara2 |
Posted on Monday, Dec 23, 2002 - 8:31 am: Hi Dr O,When we tried iv NSAIDS for lymphangitis once they had no effect at all, no reduction of swelling and definitely no pain relief but I can't say there were problems with the phenobarb as she didn't have any seizures break through. A vet explained that the drugs went around on the same blood protein and there wasn't room for them both basically. Bearing in mind that she gets the phenobarb (and bromide) morning and evening and she has 99% of her seizures in the mornings, what about if I tried an anti-inflammatory say at lunchtime when some of the phenobarb would already have been processed? I'm concerned about straining her liver with "bute" too, she has been having the anticonvulsants for nearly 4 years now which must be taking its toll. My vet says I worry too much about her liver! She looks fine and healthy with plenty of energy. A friend suggested I use oral MSM as that has an antiinflammatory effect but I don't know how the body processes that. Any ideas? At least its the Christmas holidays now and I can do more cold-water hosing for her. |
Moderator: DrO |
Posted on Monday, Dec 23, 2002 - 10:30 am: It is not uncommon for inflammatory disease from infectious cause to not be greatly effected by NSAID's. This is so consistant that this is a important diagnostic tool. The phenobarb would not block the effect of the flunixin through any mechanism I am aware of but may increase it's rate of excretion.Oral MSM is not likely to be of much use. Yes you could try giving the phenobarb and flunixin at different times. Flunixin may be a better choice because it may not be as highly protein bound as the bute. As least there is less talk about it. DrO |
New Member: Cinthy |
Posted on Sunday, May 11, 2003 - 8:27 pm: My horse's left hind leg got kicked several weeks ago resulting in swelling just above the fetlock joint. She has not been lame at all. I have given her bute, rested her, tried light riding to work it out. I then moved on to sweating and pressure wraps. This was really working until I wrapped her leg too tight resulting in a rebound in swelling much worse than the original injury. There is a man at our barn who is known to be very good and knowledgeable with horses. He recommended the old remedy of putting on an Alum (the pickling spice) paste then wrapping with vet wrap. Have you ever heard of this and is it effective at all. Do I just go back to square one with the sweating and wrapping. Please remind everyone not to wrap too tight as it causes a big problem.Cinthy Carson |
Moderator: DrO |
Posted on Monday, May 12, 2003 - 10:52 am: I do not have any experience with alum Cinthy. Our recommendations for pressure bandaging are found at Equine Diseases » First Aid » Pressure Wraps, Poultices, Cold and Heat Therapy for Swelling in Horse Legs. You will find an admonishment there about bandages that are too tight, or more often the problem: the pressure is uneven.DrO |
Member: Bara |
Posted on Monday, May 12, 2003 - 11:12 pm: My step daughter lives in alabama. she got a pony from rescue and got it in condition so she thought. the pony colicked on her so the vet gave him a shot of banamine. the pony started lowering its head and frothing at the mouth and nose with a mixture of foam and blood. this happened twice. im at the conclusion that they need to be looking at some other illness. her vet said the horse might have had an allergic reaction to the banamine. but he gave him another shot with the same reaction.my question. can a horse have an allergic reaction to banamine? |