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Adequan, Polysulfated Glycosaminoglycan (PSGAG), and their use in Horses
by Robert N. Oglesby DVM
Introduction
Introduction
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Efficacy
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Adverse Reactions
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Recommendations
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Dosage
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More Info
Adequan is advertised as being useful in the treatment of non-infectious arthritis of horses. It is a polysulfated glycosaminoglycan (PSGAG) and is chemically similar to natural mucopolysaccharides found in the cartilage of joints. In addition to PSGAG, pentosan polysulfate (PPS) (Cartrophen Vet, Pentosan Equine Injection) , and GAG peptide complex (Rumalon) belong to this same family of drugs. Also products like Chondro-Protec have popped up that have made claim to be generic forms of Adequan.
Despite early wide spread use as a intra-articular (IA) injection research indicating it may potentiate the chance of infection in the joint following administration has caused a move towards it's use through muscle injections (IM). However there have been questions as to the usefulness of this route of administration and how it compares with IA use.This article discusses the use, efficacy, and safety of Adequan and these generic drugs in horses with arthritis.
~Word Count: 1261 words (The average magazine page contains about 600 words);
~Last Updated: May 28, 2008;
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Discussions on Adequan, use in Arthritis
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Subtopics |
Posts |
Updated |
 | IM Adequan - article seems to say, doesn't work | 1 | 7 | Mar 29, 08 |
| Pentosan versus adequan | 1 | 5 | Feb 27, 08 |
| Adequan update---my mares | 1 | 8 | Aug 15, 07 |
| New Article | 1 | 1 | Mar 15, 07 |
| Adequan monthly? | 1 | 2 | Apr 25, 06 |
| Adequan IM: weekly dose vs. every 4 days? | 1 | 5 | Dec 26, 06 |
| Adequan vs generic equivalent | 1 | 2 | Sep 21, 04 |
| Adequan IM - Prevents further joint degeneration?? | 1 | 8 | May 26, 04 |
| Adequan as a preventative? | 1 | 4 | Mar 14, 06 |
| Adequan side effects | 1 | 3 | Sep 8, 03 |
| Adequan vs. Chondroprotec | 1 | 25 | Mar 9, 07 |
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