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Discussion on RVI - Rubeola virus immunomodulator
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Member:
sbower
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Posted on Thursday, May 17, 2007 - 5:02 pm:
Does anyone have any experience with this ? It was recently prescribed for my horse for back pain and it was something I haven't heard of.
According to the company (Eudaemonic} "RVI is a specific immunomodulator agent (IMA) with subvaccination levels of an inactivated rubeola virus that acts to modify the immune and inflammatory responses to alleviate Chronic Myofascial Inflammation (chronic muscle soreness) and its associated problems in the equine."
Is this something new? Dr. O could you comment on the mechanics of how this (essentially a measles vaccine?????) would reduce inflammation?
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Moderator:
DrO
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Posted on Friday, May 18, 2007 - 8:47 am:
Concerning a possible mechanism of action, you got me Shelly. Searching the last 40 years of the scientific literature for "inactivated rubeola virus muscle" turns up exactly 2 links neither or which has anything to do with treating muscle soreness. What does Eudaemonic say about this?
DrO
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Member:
sbower
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Posted on Friday, May 18, 2007 - 9:34 am:
Link to their website is https://www.eudaemonic.net/rviinformationsheet.htm Their research studies (very small ones) are there too. I'd love to know what you think. One of the studies was cited as
Vasko and McMichael J; Anti-inflammatory effects of an immuno-modulating agent. J Eq Vet Sci 8(1):77, 1988
I can't seem to find much, if this RVI works as well as they say it seems to me 20 years later there would be a larger body of proof. There may not be a market for it... maybe because one 12ml bottle of it was about $160. Bute certainly is cheaper! But if this works better and faster and won't cause ulcers it seems to me that, for the horses that don't tolerate bute well, that this would be a substitute.
As they say, the proof is in the pudding, according to them my horse should show improvement today!
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Member:
sbower
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Posted on Sunday, May 20, 2007 - 9:05 pm:
Anything?
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Moderator:
DrO
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Posted on Monday, May 21, 2007 - 8:31 am:
I see nothing on the site that gives me any confidence Shelly. Often articles in the journal so often quoted on the site published articles that were not reviewed back then, though this has improved recently.
DrO
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