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Discussion on Research Summary: eFSH Use in Mare
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Moderator: DrO
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Posted on Monday, Sep 24, 2007 - 8:39 am:
Theriogenology. 2007 Aug;68(3):429-33. Epub 2007 Jun 4. eFSH in clinical equine practice. McCue PM, LeBlanc MM, Squires EL. Colorado State University, Ft. Collins, CO 80523, and Rood and Riddle Equine Hospital, Lexington, KY 40580, United States. Equine follicle stimulating hormone (eFSH) has been used to induce follicular development in transitional mares and problem acyclic mares, as well as superovulate cycling mares. The most efficacious protocol is to administer 12.5 mg eFSH, intramuscularly, twice daily beginning 5 to 7 days after ovulation when the diameter of the largest follicle is 20 to 25 mm. Prostaglandins are to be administered on the second day of eFSH therapy. Treatment with eFSH is continued for 3 to 5 days until follicle(s) are >or=35 mm in diameter. The mare is subsequently allowed to 'coast' for 36 h, after which human chorionic gonadotropin is administered to induce ovulation.
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