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Discussion on Pentosan versus adequan

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Nicola Sturgess
New Member
Username: nicola

Post Number: 3
Registered: 1-2008
Posted on Wednesday, Feb 20, 2008 - 11:21 am:   Edit PostPrint Post

Does anyone have a view on the efficacy of Pentosan versus Adequan. I have one vet who swears by pentosan but everyone I know that has used it says it doesn't work and that this has been proven in clinical studies.
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Robert N. Oglesby DVM
Moderator
Username: dro

Post Number: 20110
Registered: 1-1997
Posted on Thursday, Feb 21, 2008 - 6:23 am:   Edit PostPrint Post

Hello Nicola,
There is no proof that pentosan polysulfate (PPS)does not have some clinical efficacy Nicola. Support for it is largely anecdotal, though some of that positive report comes from the arthritis gurus of Colorado State. Then again the work that supports IM Adequan is not written in stone. For more on what current research says on both of these drugs, recommendations for use, and dosage see the article on Adequan.
DrO
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Nicola Sturgess
New Member
Username: nicola

Post Number: 4
Registered: 1-2008
Posted on Thursday, Feb 21, 2008 - 4:57 pm:   Edit PostPrint Post

Thanks Dr O.

Will read article.

Nicola
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Laura
Member
Username: ljudkins

Post Number: 7
Registered: 5-2007
Posted on Wednesday, Feb 27, 2008 - 7:43 am:   Edit PostPrint Post

Hi Nicola,

I have used Pentosan Polysulfate and Adequan. I felt the Pentosan worked. (I ordered mine from horsemedsonline.com in Australia). I researched the drug when I had a horse with OA/DJD.

Here are a couple of articles that may help provide more background information.

Current Treatments for Traumatic Synovitis,
Capsulitis, and Osteoarthritis http://www.ivis.org/proceedings/aaep/2001/91010100180.pdf
and Evaluation of Pentosan Polysulfate http://www.equineortho.colostate.edu/pdf/pentosan_polysulfate.pdf

Is you question more FYI related or are you looking to treat something more specific?

Laura
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Laura
Member
Username: ljudkins

Post Number: 8
Registered: 5-2007
Posted on Wednesday, Feb 27, 2008 - 8:05 am:   Edit PostPrint Post

Nicola,

I can never find what I'm looking for until I have sent the information.

This is a nice summary of many things, but it discusses Adequan and Pentosan.

http://www.thehorse.com/ViewArticle.aspx?ID=10800&kw=lameness

Laura
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