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Discussion on Effectiveness of bute

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sandy waltz
Member
Username: kiwi1

Post Number: 16
Registered: 3-2007
Posted on Thursday, Jul 3, 2008 - 8:30 pm:   Edit PostPrint Post
Hi Dr. O

Very weird question but how long would the effects of one gram of bute last in a very large, say 1200 lbs. warmblood? Does it peak at 12 hours and then trail off by 24 hours? Would even one gram of bute effect such a large animal? Sorry to ask such a weird question but I've been reading conflicting information about peak effects and duration of the drug.
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Robert N. Oglesby DVM
Moderator
Username: dro

Post Number: 20953
Registered: 1-1997
Posted on Saturday, Jul 5, 2008 - 9:04 am:   Edit PostPrint Post
Yes Sandy one gram has an effect but that is not saying the same as it will achieve the desired results and larger doses can be used... Concerning once or twice daily dosing, better pain and antiinflammatory action is achieved when the 24 hour dose is divided in half and given at 12 hour intervals. It is probably less toxic that way too.
DrO
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