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Discussion on Estrol Sulfate injections for Stifle ligament

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Debra Dove
Username: 5691

Post Number: 43
Registered: 8-2006
Posted on Monday, Jul 7, 2008 - 7:08 pm:   Edit PostPrint Post

Our five year old Hanaverian experienced a right stifle lock yesterday which resolved on its own after a dose of Banamine as recommended by our veterinarian. (He experienced a leg lock at the age of two and was given two injections of almond oil and iodine at that time that seemed to do the trick till now.)

Vet exam observed intermittent locking during the exam but he is sound when unlocked. He rested yesterday in a large paddock where he can move around. He was ridden today lightly in the arena mostly in a "together frame" at the trot and then taken on a 1/2 mile cool down walk around the property bridle path.

Our vet consulted with Pioneer Veterinary in Oakdale and the vet she spoke with (who has been my vet with our older horse) is recommending a course of estrol sulfate injections to "tighten the ligament".

Am curious to know more about this drug and if anyone else has used or is using this regime for the same reason and what the success rate is for helping reduce this mechanical problem.

It was felt that an xray and ultrasound were not necessary at this time since the pre-purchase exams were within normal limits three months ago.

In the meantime, we are to continue to ride daily keeping the horse in a more collected frame. He is young, so we are striving to find the balance between keeping him "together" when doing arena work, incline trotting and ground poles and letting him stretch and relax on trail rides and during breaks. His weight is good according to our vet and he is on a seven week shoeing schedule. He has certainly grown and filled out in the three months we have had him.. Any chance this could be a "growing pain" blip?

Smiles and Thanks,
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Robert N. Oglesby DVM
Username: dro

Post Number: 20977
Registered: 1-1997
Posted on Tuesday, Jul 8, 2008 - 9:10 am:   Edit PostPrint Post

Hello Debra,
As to a growing blip yes that certainly is a possibility. There is no good research on estrol or estradiol injections for stifle lock but you will find more on this and other information in the article Diseases of Horses » Lameness » Diseases of the Upper Rear Limb » Stifle Lameness » Stifle Lock: Upward Fixation of the Patella.
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J.R. Griffin
New Member
Username: 01griff

Post Number: 2
Registered: 6-2010
Posted on Friday, Jun 18, 2010 - 10:30 am:   Edit PostPrint Post


Why would Theelin be given to a 4 YO TB gelding prior to a race?
I did some Google research and find that it is a combination of estrogin and progesterone used to treat menopause or estrogendeficiency side effects in humans..

Could not find anything on equine use of Theelin
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Username: rtrotter

Post Number: 832
Registered: 4-2008
Posted on Friday, Jun 18, 2010 - 8:14 pm:   Edit PostPrint Post


You might want to put your question under its own discussion, but in the meantime, you probably won't find much on equine use of this particular drug name since it a human use drug. However, this combination of estrogen and progesterone is used in horses. This is only conjecture on my part, but having been around racehorses for 35+ years, I'll take a shot at this, and leave the rest of it to Dr. O.

While usually used in mares to knock them out of heat for racing, in geldings it may be used as an attitude enhancer if they are sour or mean or as an adjunct medication (especially the estrogen part), if they bleed whether on or off lasix.It is thought that the estrogen helps prevent bleeding by making lung cells more elastic.

Please note that Dr. O may have a completely different take on this than I do. I am going by my knowledge of and experience in the racehorse industry.

I believe that good equine management replaces many of the reasons people use drugs on their racehorses and if more horses spent more time out of their stalls(turned out) than in them, they would be a lot happier(horses and people)the racehorse vets wouldn't be, because pre-racing horses is their bread and butter, but that is a discussion for another time and place.

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Robert N. Oglesby DVM
Username: dro

Post Number: 24902
Registered: 1-1997
Posted on Saturday, Jun 19, 2010 - 2:28 pm:   Edit PostPrint Post

Hello JR,
Let me get you started off right. You will probably get more responses if you start your own discussion rather than post at the bottom of another member's discussion. Each discussion is "owned" by the original poster and all replies in that discussion should either directly or indirectly address the concerns of the original poster.

To start your own discussion using the navigation bar at the top of this page to back up one page. This will be a Article Page who at the bottom has a list of already present discussions. You will find the "Start New Discussion" button at the bottom of this page.

This is as good a place as any for this discussion and if you will back up one page using the navigation bar above you will find the Start New Discussion button at the bottom of the list of already existing discussions.

Thank you for your help with keeping organized and easily searchable.
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