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Discussion on Previcox for horse with laminitis

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Chris Mills in NC
Username: chrism

Post Number: 1272
Registered: 4-1999
Posted on Tuesday, Nov 8, 2011 - 8:12 pm:   Edit PostPrint Post

My 28 year old mare has had her first known bout of laminitis, likely related to metabolic changes. She has been on high dose bute for several weeks, is now in support shoes and we've been lowering the bute level, but got stuck at 1 gram per day, which, even if split, doesn't appear to give her enough comfort consistently. Two sets of x-rays show slight changes, but no worsening in about a 2 week period.

We are trying the smaller 57 mg Previcox pill daily to see if it is more helpful to her.

I've been reading about Previcox and have a question re dosage - how in the world can a little pill that helps a small dog such as a dachshund help a horse that weighs 1000 lbs.?

Also, does anyone have a "best price" source that they'd recommend should I need to continue my old gal on this?

Thanks in advance.
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Username: frances

Post Number: 1223
Registered: 3-2004
Posted on Wednesday, Nov 9, 2011 - 1:18 am:   Edit PostPrint Post

It appears that dogs metabolize firocoxib much faster than horses, and that's why horses require so much less for the same effect. Good for us, right?!
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Vicki Z
Username: vickiann

Post Number: 2536
Registered: 3-2005
Posted on Wednesday, Nov 9, 2011 - 8:50 am:   Edit PostPrint Post

Have used that amount of Previcox for a horse with laminitis who weighs somewhere between 900 and 950.

It seemed to take a bit longer for the Previcox to build up in the system (2 - 3 days) than with Bute but it worked really well once we got going with it.

One big benefit was it was much easier on my horse's stomach and mixing the tablet with a few pellets of food in a pan held in my hand made it so easy to get the medication into the horse. Being it is a chewable tablet it is very readily eaten by horses, in my experiences.

I also used this dosage for several days on a larger horse (about 1170) who was very painful after having been trimmed way too short. It worked great.

I just bought the Previcox through the Vet but I imagine you could get a good price on the Internet through someone like

Good luck with your horse with her recovery.
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Robert N. Oglesby DVM
Username: dro

Post Number: 26043
Registered: 1-1997
Posted on Wednesday, Nov 9, 2011 - 2:31 pm:   Edit PostPrint Post

Hello Chris,
It really is a combination of factors that make the relatively small dose effective in horses but LL's point is the most important. Firocoxib has a half life of 30 hours in the horse. With this is mind Vicki's experience makes sense because when first started there are several days of accumulation while blood levels rise to the point that the amount lost in a day equals the daily dosage.
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