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Discussion on The use of HCG

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Adrienne Lambert
Posted on Saturday, Mar 4, 2000 - 10:48 pm:   Edit PostPrint Post

We have been told to use the drug HCG, to help our "slow" stallion, reccomended was 2 hrs and then 1 hr before breeding, the use on mares was after the 4th day to give HCG to promote the folicle to "drop". I guess I would like your input on this, and also the long term effect this may or may not cause.
Thankyou
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Robert N. Oglesby DVM
Posted on Sunday, Mar 5, 2000 - 11:39 am:   Edit PostPrint Post

What breed and how old is your stallion Adrienne? This is not a standard use for this drug but is founded in good scientific research. It is known that hCG causes a marked increase in testosterone in stallions but the short and long term benefits and problems have not been well studied. Currently I know of no contraindications. This is a pretty good paper on the subject:

Prolonged effect of a single injection of human chorionic gonadotrophin on plasma testosterone and oestrone sulphate concentrations in mature stallions.

Cox JE, Redhead PH
Department of Veterinary Clinical Science, University of Liverpool Veterinary Field Station, Neston, South Wirral.

The long term effect of a single injection of 6,000 iu of human chorionic gonadotrophin (hCG) was studied in two pony stallions. Peripheral plasma samples were analysed for testosterone and oestrone sulphate. Testosterone concentrations were markedly elevated for five days after injection in both stallions. No adverse effects of these high concentrations were observed on concentrations later in the experiment. There was an initial increase in oestrone sulphate in one stallion, after which concentrations decreased to below pre-injection levels. The other stallion (whose initial oestrone sulphate concentrations were somewhat higher) showed no rise in response to hCG but did show a significant decline from five days after injection. Whether this suppression is an effect of the high testosterone concentrations remains to be determined.

Adrienne if you use this technique I would love to know the dosage you use, the rounte of administration, and the effect you see. Thanks!
DrO
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Adrienne Lambert
Posted on Sunday, Mar 5, 2000 - 1:23 pm:   Edit PostPrint Post

The Stallion is a 5 Yr Old QH, he has always been a VERY slow breeder, the dosage we were told to give is 3 cc, 2 hrs and then 1 hr before breeding.for a total of 6cc. This stallion was purchased thru a sale in Ok. as a 2 yr old in a partnership dispersal, and had not been shown at that time. He has been shown in Halter by ourselves and by our trainer. The first being local shows by us with a couple of breed shows thrown in, then to the trainers for the end of the 3 yr old yr and beginning of the 4th, he was also to be taught to be collected. He recieved 20 open points, several by the trainer, the balance by us. He did not recieve any muscle enhancing drugs by us, but we have no idea how or what he recieved there. We are expecting approx 18 foals, both outside clients and our own, some of which are arleady on the ground. He has a very desireable pedigree but we don't want to "over book" him. He does collect and live cover. Any comments and suggestions will be welcomed.
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Sally Hayward
Posted on Thursday, Mar 23, 2000 - 10:38 pm:   Edit PostPrint Post

I have a breeding question. Last year I gave my mare an injection of HCG to induce ovulation in order to AI her. Since giving this mare the HCG injection she has never cycled again. She shows only small CL's. As of now she has not cycled yet this Spring. This is also a maiden mare who cycled like clock work prior to the HCG. Any ideas in bringing this mare around again.
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Posted on Friday, Mar 24, 2000 - 2:37 pm:   Edit PostPrint Post

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