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| Author |
Message |
    
Pennie Shewmaker (Cactus)
| | Posted on Monday, Aug 28, 2000 - 8:10 am: |   |
I have read the information available on Dexamethasone but am still a little lost. Wanting to know if you can give bute and dex. together as an antiinflammatory? I have an older horse that after a lot of changing around on her feet and some other things is finally approximately 95 - 98% sound. She is 16 years old so the vet has told me getting her 100% is probably not going to happen. I currently give her 1 bute pill a day but was wondering about giving her 2 or 3 bute pills before competing and then giving her 5 c.c. of dexamethsone. I understand the dex is something you cannot give too often, just wanting to use it every few months to help her out a little?
Your opinions on this? |
Robert N. Oglesby DVM (Dro)
| | Posted on Monday, Aug 28, 2000 - 8:11 pm: | |
Combing the bute and the dex will increase your chances of gastrointestinal inflammation. We know older horses clear bute more slowly so can increase the chance of accumulation. However I use 2 grams per 1000 lbs twice daily occasionally for a day or three. At her age 1 twice daily for short periods would not cause problems in the great majority of horses. If arthritis is the problem are you using the condroprotective oral supplements?
DrO |
Eveo (Eveo)
| | Posted on Tuesday, Aug 29, 2000 - 1:01 am: | |
Pennie--I have a 25-yr-old mare who has ringbone. She is buted (2 grams) for farrier visits and an occasional stroll, and also has been getting bute (1 gram) 4 days on and 3 days off for general comfort. My vet says that taking her off the bute for 3 days will let her system clear the bute and, I hope, prevent complications.
I, however, hate to see her uncomfortable so have just started her on a yucca & devils' claw combination. The yucca is supposed to be a precursor of cortisone, which is supposed to lead to reduced inflammation. The devils' claw is for pain. We've just completed the loading period. I can't tell if it's "working." She is thundering around the pasture more; but she stands around with her "worse" foot pointed, too.
If I see a definite positive effect, I'll report back. |
Pennie Shewmaker (Cactus)
| | Posted on Tuesday, Aug 29, 2000 - 7:22 am: | |
Thank you for the information. I have already dealt with ulcers so I am all to familiar with the expense and problems associated with them. At the time my mare had the ulcers I had never so much as given her one bute pill. But we treated it with Gastrogard and I have changed my feeding and turnout program and there has been no sign for like a year. I do feed all the supplements, like MSM, and Cortaflex, religiously! I was just trying to determine the affects of the dex with the bute. I can understand now that I would increase the chances of an ulcer. Definately something to think about. Possibly this is something that I could do only when absolutely necessary (maximum of a few times a year) and there not be any problems. I get complete blood tests done every so many months just to keep check on any problems we may be able to notice.
Thanks. And please let me know how that all natural supplement works. |
Jill Jasper (Playinmy)
| | Posted on Tuesday, Apr 24, 2001 - 5:16 pm: | |
try quadrisol (vedaprofen) instead of bute...it is safer....for long term use |
Robert N. Oglesby DVM (Dro)
| | Posted on Wednesday, Apr 25, 2001 - 9:57 am: | |
Hello Jill,
Quadrisol or vedaprofen is a NSAID of the same class of drugs as keto- and carprofen. We have information available on these drugs at : Equine Medications and Nutriceuticals: Anti-inflammatories, Steroids, and Arthritis Treatment: An Overview of NSAID's.
This medication is not likely to be effective in situations where bute is not. It may have safety benefits or be more effective at recommneded doses. On the otherhand I cannot find information directly on vedaprofen to support or contradict this. I would be interested in any information you have on the subject.
DrO |
Stephanie McCarron
New Member
Username: Splendid
Post Number: 1
Registered: 1-2003
| | Posted on Thursday, Jan 30, 2003 - 9:18 pm: | |
Hello,
I own a horse and show him in the jumper division at major horse shows. I give him injectable dex to calm him down. I usually start with 8cc the night before and then decrease as the week goes on. I was wondering how you compare the injectable dex to the granuales. I was told you just use a packet the morning before but I was wondering for more specific answers.
Thanks, Stevie |
Robert N. Oglesby DVM
Moderator
Username: Dro
Post Number: 7701
Registered: 1-1997
| | Posted on Friday, Jan 31, 2003 - 4:15 am: | |
I have never seen any reports about the pharmacology of oral dexamethasone so do not really have any good thoughts. I suspect that the oral product is well absorbed but will be slower to get into the system, have lower peak blood levels but persist longer in the blood. But what the numerical differences are I just do not know. In general because of the ridiculous price of the granules I use the injectable orally, squirting it on the food.
DrO |
